Mối liên hệ giữa sin3a và sự ứng dụng của toán học trong các tình huống thực tế.

function. Acts as a transcriptional repressor. Corepressor for REST. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities ... ▽ Description. SAP130 is a subunit of the histone deacetylase (see HDAC1; 601241)-dependent SIN3A (607776) corepressor complex (Fleischer et al., 2003). Here, we define a critical role for the corepressor SIN3A in memory and synaptic plasticity, showing that postnatal neuronal deletion of Sin3a enhances ... Protein complexes containing SIN3A act as histone deacetylase (see HDAC1; 601241)-dependent corepressors. SIN3A contains multiple protein-protein ... Jun 14, 2019 ... Abstract. STAT3 can mediate epigenetic silencing of tumor suppressor genes (TSG). However, little is known about the molecular mechanisms ... Aug 2, 2018 ... Our data suggest that Fam60a is required for proper embryogenesis, at least in part as a result of its regulation of DNA methylation at specific gene promoters. Sin3A associated protein 30 [Source:HGNC Symbol;Acc:HGNC:10532]. Ensembl ID. ENSG00000164105. Bio databases IDs, NCBI: 8819 Ensembl: ENSG00000164105. Aliases ... Sep 14, 2020 ... In particular, the researchers identified several genes that Sin3a appeared to regulate, including some associated with protein transport, ... Reduction of Sin3A expression by RNA interference specifically inhibits estrogen-induced repression of ESR1. Furthermore, an estrogen-responsive interaction ... Feb 18, 2020 ... A ) Structure of murine Sin3a locus with exon 4 highlighted. · B ) Sin3aNH mice have decreased SIN3A protein levels (arrows) in the hippocampus ...