Mối liên hệ giữa sin3a và các vấn đề về tâm lý học (ví dụ, nghiên cứu về nhịp sinh học).

Recent study has identified that haploinsufficiency of SIN3A (chromosome 15q24.2) is associated with mild syndromic intellectual disability. This phenotype ... SIN3A-related syndrome is a genetic condition, which means that it is caused by variants in genes. Our genes contain the instructions, or code, that tell our ... Jul 15, 2015 ... Here, we describe the mechanism of assembly of the mammalian Sin3L/Rpd3L complex facilitated by Sds3, a conserved subunit deemed critical for proper assembly. Product Information. 14638-1-AP targets SIN3A in WB, IF/ICC, IP, CoIP, ELISA applications and shows reactivity with human, mouse, rat samples. Aug 1, 2023 ... SIN3A defects associated with syndromic congenital hypogonadotropic hypogonadism: an overlap with Witteveen-Kolk syndrome. Feb 23, 2018 ... However, the increase in maternal SIN3A does not play a role in the minor ZGA, as depleting maternal SIN3A had no effect on global transcription ... Jan 12, 2021 ... Abstract. Witteveen-Kolk syndrome (OMIM 613406) is a recently defined neurodevelopmental syndrome caused by heterozygous loss-of-function ... Mar 22, 2023 ... pSID co-localizes with Sin3A and interference with PAH2-mediated Sin3A functions by pSID is shown by disruption of Sin3A-MAD1 interactions ... SIN3A (SIN3 Transcription Regulator Family Member A) is a Protein Coding gene. Diseases associated with SIN3A include Witteveen-Kolk Syndrome and Chromosome ... Here, we show that FOXK2 binds to the SIN3A and PR-DUB complexes. The PR-DUB complex contains the important tumour suppressor protein, the deubiquitinase ...