Mối liên hệ giữa sin3a và các vấn đề về công nghệ và đổi mới.

Jun 14, 2019 ... Abstract. STAT3 can mediate epigenetic silencing of tumor suppressor genes (TSG). However, little is known about the molecular mechanisms ... Jul 15, 2015 ... Here, we describe the mechanism of assembly of the mammalian Sin3L/Rpd3L complex facilitated by Sds3, a conserved subunit deemed critical for proper assembly. Feb 3, 2025 ... ... Sin3a as a novel transcriptional regulator of β-cell mass adaptation. β-Cell–specific Sin3a knockout animals showed profound diabetes due to ... Jan 1, 2018 ... t(15;21) translocations leading to the concurrent downregulation of RUNX1 and its transcription factor partner genes SIN3A and TCF12 in myeloid ... Aug 14, 2017 ... We demonstrated that the FOXN3-NEAT1-SIN3A complex promotes EMT and invasion of breast cancer cells in vitro as well as dissemination and ... Unfollow This Gene ... Click here to learn more about how to cite ClinGen and to see a list of the external resources utilized. The information on this website is ... Jun 13, 2020 ... Let c=cos(A), s=sin(A), C=cos(2A), and S=sin(2A). Then. cos(3A)=Cc−Ssandsin(3A)=Sc+sC. so the numerator on the LHS is. Aug 1, 2023 ... SIN3A defects associated with syndromic congenital hypogonadotropic hypogonadism: an overlap with Witteveen-Kolk syndrome. Fam60a defines a variant Sin3a‐Hdac complex in embryonic stem cells required for self‐renewal. The EMBO Journal. Sin3a is the central scaffold protein of ... Here, we define a critical role for the corepressor SIN3A in memory and synaptic plasticity, showing that postnatal neuronal deletion of Sin3a enhances ...