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Feb 3, 2025 ... ... Sin3a as a novel transcriptional regulator of β-cell mass adaptation. β-Cell–specific Sin3a knockout animals showed profound diabetes due to ... Sin3a deletion in mice causes CDH, lung hypoplasia, defects in cell cycling, and pulmonary hypertension. • Use Sin3a genetic targets as a guide to improve lung ... ... Sin3A, Rab40C, Rad50, and Ube2i were necessary for both AHR expression and ... Sin3A, from which we found that Sin3A physically associates with the 5 ... Jun 14, 2019 ... Abstract. STAT3 can mediate epigenetic silencing of tumor suppressor genes (TSG). However, little is known about the molecular mechanisms ... Feb 9, 2024 ... We observe that Sin3A protein is enriched at replicating DNA in the presence of hydroxyurea. In this situation, Sin3A-depleted cells show ... Nov 1, 2014 ... ... Sin3A Associated Protein 130 (SAP130). 2. Previous1Next. Citation. Dessen P. SAP130 (Sin3A associated protein 130). Atlas Genet Cytogenet Oncol ... A few children are known to have inherited a pathogenic variant of the SIN3A gene form a mildly affected parent. The risk of having another child affected by a ... Oct 12, 2018 ... ... Sin3a−Hdac complex, at which point it introduces chemical modifications to the DNA that directly influence whether adjacent genes are ... View other "Sin3a" antibodies ; Polyclonal · The immunogen is a synthetic peptide directed towards the middle region of mouse SIN3A · Expected reactivity: Mouse. Here, we define a critical role for the corepressor SIN3A in memory and synaptic plasticity, showing that postnatal neuronal deletion of Sin3a enhances ...
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