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May 8, 2018 ... LSD1 coordinates with the SIN3A/HDAC complex and maintains sensitivity to chemotherapy in breast cancer Jan 24, 2022 ... Conclusions. Our studies revealed that Sin3a was a novel mediator of MET during early reprogramming, where Sin3a functioned as an epigenetic ... Aug 14, 2017 ... We demonstrated that the FOXN3-NEAT1-SIN3A complex promotes EMT and invasion of breast cancer cells in vitro as well as dissemination and ... Jul 15, 2015 ... Here, we describe the mechanism of assembly of the mammalian Sin3L/Rpd3L complex facilitated by Sds3, a conserved subunit deemed critical for proper assembly. Unfollow This Gene ... Click here to learn more about how to cite ClinGen and to see a list of the external resources utilized. The information on this website is ... Oct 2, 2018 ... Here we report the identification of a highly conserved SID in the 5-methylcytosine dioxygenase, Tet1 (Tet1-SID), which interacts directly with the PAH1 domain ... A few children are known to have inherited a pathogenic variant of the SIN3A gene form a mildly affected parent. The risk of having another child affected by a ... View SIN3A Antibody (NB100-2253) validated in 2 species & 2 applications from Novus Biologicals. Sin3a plays a critical role in the maintenance of Treg identity and function and is essential for the expression and stability of Foxp3. Witteveen-Kolk syndrome is a rare neurodevelopmental disorder comprising intellectual disability, developmental delay and dysmorphic facial features