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Feb 14, 2022 ... ... SIN3A protein. Suppression of focal adhesion kinase and SIN3A also induces apoptosis and prevents tumor progression, suggesting that they ... Sin3a deletion in mice causes CDH, lung hypoplasia, defects in cell cycling, and pulmonary hypertension. • Use Sin3a genetic targets as a guide to improve lung ... Oct 2, 2018 ... Here we report the identification of a highly conserved SID in the 5-methylcytosine dioxygenase, Tet1 (Tet1-SID), which interacts directly with the PAH1 domain ... Jul 1, 2014 ... to Sin3A whereas 3-Cl-AHPC exposure decreased the level of. Sin3A protein at 48 h in Western blot (Fig. 4A). Exposure of cells to 3-Cl-AHPC ... Jun 28, 2017 ... Sin3a is a central component of a class of histone deacetylase‐containing transcriptional co‐regulatory complexes. In this issue of The EMBO ... SIN3A (SIN3 Transcription Regulator Family Member A) is a Protein Coding gene. Diseases associated with SIN3A include Witteveen-Kolk Syndrome and Chromosome ... function. Acts as a transcriptional repressor. Corepressor for REST. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities ... Jul 15, 2015 ... Here, we describe the mechanism of assembly of the mammalian Sin3L/Rpd3L complex facilitated by Sds3, a conserved subunit deemed critical for proper assembly. Product Information. 14638-1-AP targets SIN3A in WB, IF/ICC, IP, CoIP, ELISA applications and shows reactivity with human, mouse, rat samples. Dec 10, 2007 ... Covalent modification of histones regulates chromatin structure and gene expression. Sin3A mediates the association of histone deacetylase ...