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Nov 1, 2014 ... ... Sin3A Associated Protein 130 (SAP130). 2. Previous1Next. Citation. Dessen P. SAP130 (Sin3A associated protein 130). Atlas Genet Cytogenet Oncol ... Jan 12, 2021 ... Abstract. Witteveen-Kolk syndrome (OMIM 613406) is a recently defined neurodevelopmental syndrome caused by heterozygous loss-of-function ... SIN3A (D9D6) Rabbit mAb recognizes endogenous levels of total SIN3A protein. Based on protein sequence, this antibody is not predicted to cross-react with SIN3B ... Reduction of Sin3A expression by RNA interference specifically inhibits estrogen-induced repression of ESR1. Furthermore, an estrogen-responsive interaction ... ... SIN3A and MAN2C1 resulting in Witteveen-Kolk syndrome ... This deletion is anticipated to result in production of a chimeric SIN3A::MAN2C1 protein which would ... Jan 24, 2022 ... Conclusions. Our studies revealed that Sin3a was a novel mediator of MET during early reprogramming, where Sin3a functioned as an epigenetic ... ... Sin3A corepressor complex and targets Sin3A. SAP30L interacts with members of the Sin3A corepressor complex and targets Sin3A to the nucleolus. Nucleic Acids ... Jul 15, 2015 ... Here, we describe the mechanism of assembly of the mammalian Sin3L/Rpd3L complex facilitated by Sds3, a conserved subunit deemed critical for proper assembly. Recent study has identified that haploinsufficiency of SIN3A (chromosome 15q24.2) is associated with mild syndromic intellectual disability. This phenotype ... Feb 23, 2018 ... However, the increase in maternal SIN3A does not play a role in the minor ZGA, as depleting maternal SIN3A had no effect on global transcription ...
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