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The Effect of Sin3a Complex on Cell Cycle and Cell Death in Mouse Embryonic Stem Cells. Date. 2019-09-29. Author. Güven, Gözde Terzi Çizmecioğlu, Nihal. Mar 22, 2023 ... pSID co-localizes with Sin3A and interference with PAH2-mediated Sin3A functions by pSID is shown by disruption of Sin3A-MAD1 interactions ... Witteveen-Kolk syndrome (WITKOS) is an autosomal dominant disorder with characteristic distinctive facial features, microcephaly, short stature, and mildly ... Recent study has identified that haploinsufficiency of SIN3A (chromosome 15q24.2) is associated with mild syndromic intellectual disability. This phenotype ... Sin3A associated protein 30 [Source:HGNC Symbol;Acc:HGNC:10532]. Ensembl ID. ENSG00000164105. Bio databases IDs, NCBI: 8819 Ensembl: ENSG00000164105. Aliases ... ▽ Description. SAP130 is a subunit of the histone deacetylase (see HDAC1; 601241)-dependent SIN3A (607776) corepressor complex (Fleischer et al., 2003). Description. Sin3A is encoded by this gene is a transcriptional regulatory protein. It contains paired amphipathic helix (PAH) domains, which are important ... We demonstrate that SIN3A is required for TCDD induction of the CYP1A1 protein in Hepa-1 cells but not for expression of the aryl hydrocarbon receptor protein. Reduction of Sin3A expression by RNA interference specifically inhibits estrogen-induced repression of ESR1. Furthermore, an estrogen-responsive interaction ... SIN3A-related syndrome is a genetic condition, which means that it is caused by variants in genes. Our genes contain the instructions, or code, that tell our ...
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