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Here, we show that FOXK2 binds to the SIN3A and PR-DUB complexes. The PR-DUB complex contains the important tumour suppressor protein, the deubiquitinase ... Sep 14, 2020 ... In particular, the researchers identified several genes that Sin3a appeared to regulate, including some associated with protein transport, ... Jun 14, 2019 ... Abstract. STAT3 can mediate epigenetic silencing of tumor suppressor genes (TSG). However, little is known about the molecular mechanisms ... View Sin3a /Sin3a<+> Trp53 /Trp53 involves: 129S2/SvPas * C57BL/6 * FVB: phenotypes, images, diseases, and references. File:Protein SIN3A PDB 1g1e.png. Size of this preview: 702 × 599 pixels ... SIN3A protein. Based on PyMOL rendering of PDB [http://www.pdb.org/pdb ... May 3, 2013 ... Establishment of this gene variant database (LSDB) was supported by the Leiden University Medical Center (LUMC), Leiden, Nederland. Date created ... A few children are known to have inherited a pathogenic variant of the SIN3A gene form a mildly affected parent. The risk of having another child affected by a ... Sin3a deletion in mice causes CDH, lung hypoplasia, defects in cell cycling, and pulmonary hypertension. • Use Sin3a genetic targets as a guide to improve lung ... Apr 18, 2020 ... Share your videos with friends, family, and the world. Witteveen-Kolk syndrome (WITKOS) is an autosomal dominant disorder with characteristic distinctive facial features, microcephaly, short stature, and mildly ...