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Jan 1, 2018 ... t(15;21) translocations leading to the concurrent downregulation of RUNX1 and its transcription factor partner genes SIN3A and TCF12 in myeloid ... Apr 18, 2020 ... Share your videos with friends, family, and the world. Feb 27, 2024 ... Provided the recent observation that the SIN3A histone deacetylase complex reduces transcription-replication conflicts, we explore the role of ... May 25, 2024 ... Gene name - Sin3A. Synonyms - Cytological map position - 49B5-49B7. Function - Transcription factor; Chromatin protein. Dec 10, 2007 ... Covalent modification of histones regulates chromatin structure and gene expression. Sin3A mediates the association of histone deacetylase ... Protein complexes containing SIN3A act as histone deacetylase (see HDAC1; 601241)-dependent corepressors. SIN3A contains multiple protein-protein ... HDAC1 activity [29] and the Sin3A complex [30] are also required for full transcriptional activity of interferon-α responsive genes and Nanog promoter, ... Jan 24, 2025 ... BAHCC1 antagonizes SIN3A histone deacetylation and positively regulates the expression of genes that are important for growth and migration-related processes. Feb 9, 2024 ... We observe that Sin3A protein is enriched at replicating DNA in the presence of hydroxyurea. In this situation, Sin3A-depleted cells show ... View other "Sin3a" antibodies ; Polyclonal · The immunogen is a synthetic peptide directed towards the middle region of mouse SIN3A · Expected reactivity: Mouse.