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Witteveen-Kolk syndrome (WITKOS) is an autosomal dominant disorder with characteristic distinctive facial features, microcephaly, short stature, and mildly ... Aug 1, 2023 ... SIN3A defects associated with syndromic congenital hypogonadotropic hypogonadism: an overlap with Witteveen-Kolk syndrome. Reduction of Sin3A expression by RNA interference specifically inhibits estrogen-induced repression of ESR1. Furthermore, an estrogen-responsive interaction ... ... SIN3A and MAN2C1 resulting in Witteveen-Kolk syndrome ... This deletion is anticipated to result in production of a chimeric SIN3A::MAN2C1 protein which would ... Dec 10, 2007 ... Covalent modification of histones regulates chromatin structure and gene expression. Sin3A mediates the association of histone deacetylase ... 4 days ago ... SIN3A, generally regarded as a transcriptional repressor, is required for induction of gene transcription by the aryl hydrocarbon receptor. Description. Sin3A is encoded by this gene is a transcriptional regulatory protein. It contains paired amphipathic helix (PAH) domains, which are important ... SIN3A (SIN3 Transcription Regulator Family Member A) is a protein coding gene located on human chromosome 15q24.2. SIN3A is also known as WITKOS. SIN3ASIN3 transcription regulator family member A · SFARI Gene Score · Autism Reports / Total Reports · Rare Variants / Common Variants · Aliases · Associated ... Jun 13, 2020 ... Let c=cos(A), s=sin(A), C=cos(2A), and S=sin(2A). Then. cos(3A)=Cc−Ssandsin(3A)=Sc+sC. so the numerator on the LHS is.
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