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Jun 14, 2019 ... Abstract. STAT3 can mediate epigenetic silencing of tumor suppressor genes (TSG). However, little is known about the molecular mechanisms ... Jul 15, 2015 ... Here, we describe the mechanism of assembly of the mammalian Sin3L/Rpd3L complex facilitated by Sds3, a conserved subunit deemed critical for proper assembly. View Sin3a /Sin3a<+> Trp53 /Trp53 involves: 129S2/SvPas * C57BL/6 * FVB: phenotypes, images, diseases, and references. Feb 27, 2024 ... Provided the recent observation that the SIN3A histone deacetylase complex reduces transcription-replication conflicts, we explore the role of ... May 3, 2013 ... Establishment of this gene variant database (LSDB) was supported by the Leiden University Medical Center (LUMC), Leiden, Nederland. Date created ... May 8, 2018 ... LSD1 coordinates with the SIN3A/HDAC complex and maintains sensitivity to chemotherapy in breast cancer Jun 28, 2017 ... Sin3a is a central component of a class of histone deacetylase‐containing transcriptional co‐regulatory complexes. In this issue of The EMBO ... SIN3A ... Paired amphipathic helix protein Sin3a is a protein that in humans is encoded by the SIN3A gene. SIN3A. Available structures. PDB, Ortholog ... We demonstrate that SIN3A is required for TCDD induction of the CYP1A1 protein in Hepa-1 cells but not for expression of the aryl hydrocarbon receptor protein. View other "Sin3a" antibodies ; Polyclonal · The immunogen is a synthetic peptide directed towards the middle region of mouse SIN3A · Expected reactivity: Mouse.
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