Công nghệ dựa trên các nguyên tắc khoa học, trong đó toán học đóng vai trò then chốt.

Aug 14, 2017 ... We demonstrated that the FOXN3-NEAT1-SIN3A complex promotes EMT and invasion of breast cancer cells in vitro as well as dissemination and ... Jun 28, 2017 ... Sin3a is a central component of a class of histone deacetylase‐containing transcriptional co‐regulatory complexes. In this issue of The EMBO ... Feb 9, 2024 ... We observe that Sin3A protein is enriched at replicating DNA in the presence of hydroxyurea. In this situation, Sin3A-depleted cells show ... Jan 12, 2021 ... Abstract. Witteveen-Kolk syndrome (OMIM 613406) is a recently defined neurodevelopmental syndrome caused by heterozygous loss-of-function ... His-Sin3a-115-212(pL01) (Plasmid #124386) Purpose: E.Coli produced SIN3A PAH1 purified by FPLC nickel column. Depositing Lab: Shaun Cowley. Protein complexes containing SIN3A act as histone deacetylase (see HDAC1; 601241)-dependent corepressors. SIN3A contains multiple protein-protein ... File:Protein SIN3A PDB 1g1e.png. Size of this preview: 702 × 599 pixels ... SIN3A protein. Based on PyMOL rendering of PDB [http://www.pdb.org/pdb ... Witteveen-Kolk syndrome (WITKOS) is an autosomal dominant disorder with characteristic distinctive facial features, microcephaly, short stature, and mildly ... Jun 14, 2019 ... Abstract. STAT3 can mediate epigenetic silencing of tumor suppressor genes (TSG). However, little is known about the molecular mechanisms ... Feb 14, 2022 ... ... SIN3A protein. Suppression of focal adhesion kinase and SIN3A also induces apoptosis and prevents tumor progression, suggesting that they ...