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Jun 14, 2019 ... Abstract. STAT3 can mediate epigenetic silencing of tumor suppressor genes (TSG). However, little is known about the molecular mechanisms ... SIN3A (SIN3 Transcription Regulator Family Member A) is a protein coding gene located on human chromosome 15q24.2. SIN3A is also known as WITKOS. Oct 25, 2017 ... Explanation: Here is a Second Method to solve the Problem. We know the following Identities : cos3A=4cos3A−3cosA,and,sin3A=3sinA−4sin3A. ... =The ... Here, we show that FOXK2 binds to the SIN3A and PR-DUB complexes. The PR-DUB complex contains the important tumour suppressor protein, the deubiquitinase ... View Sin3a /Sin3a<+> Trp53 /Trp53 involves: 129S2/SvPas * C57BL/6 * FVB: phenotypes, images, diseases, and references. Feb 3, 2025 ... ... Sin3a as a novel transcriptional regulator of β-cell mass adaptation. β-Cell–specific Sin3a knockout animals showed profound diabetes due to ... Feb 27, 2024 ... Provided the recent observation that the SIN3A histone deacetylase complex reduces transcription-replication conflicts, we explore the role of ... Witteveen-Kolk syndrome (WITKOS) is an autosomal dominant disorder with characteristic distinctive facial features, microcephaly, short stature, and mildly ... Recent study has identified that haploinsufficiency of SIN3A (chromosome 15q24.2) is associated with mild syndromic intellectual disability. This phenotype ... Witteveen-Kolk syndrome (WITKOS) is an autosomal dominant disorder with characteristic distinctive facial features, microcephaly, short stature, and mildly ...