Việc sử dụng các mô hình toán học trong các ứng dụng thực tế cần được thực hiện một cách có trách nhiệm.

... Sin3A/Rpd3, via yet unknown mechanisms. Here, we identified Snr1and Mod(mdg4) as essential for dhd expression and investigated how these epigenomiceffectors ... Feb 9, 2024 ... We observe that Sin3A protein is enriched at replicating DNA in the presence of hydroxyurea. In this situation, Sin3A-depleted cells show ... These results demonstrate key functional differences between SIN3 paralogs in regulating the process of breast cancer metastasis. May 3, 2013 ... Establishment of this gene variant database (LSDB) was supported by the Leiden University Medical Center (LUMC), Leiden, Nederland. Date created ... SIN3A-related syndrome is a genetic condition, which means that it is caused by variants in genes. Our genes contain the instructions, or code, that tell our ... Jan 24, 2025 ... BAHCC1 antagonizes SIN3A histone deacetylation and positively regulates the expression of genes that are important for growth and migration-related processes. Feb 27, 2024 ... Provided the recent observation that the SIN3A histone deacetylase complex reduces transcription-replication conflicts, we explore the role of ... Here, we show that FOXK2 binds to the SIN3A and PR-DUB complexes. The PR-DUB complex contains the important tumour suppressor protein, the deubiquitinase ... Description. Sin3A is encoded by this gene is a transcriptional regulatory protein. It contains paired amphipathic helix (PAH) domains, which are important ... HDAC1 activity [29] and the Sin3A complex [30] are also required for full transcriptional activity of interferon-α responsive genes and Nanog promoter, ...