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Recent study has identified that haploinsufficiency of SIN3A (chromosome 15q24.2) is associated with mild syndromic intellectual disability. This phenotype ... These results demonstrate key functional differences between SIN3 paralogs in regulating the process of breast cancer metastasis. List of variants reported for SIN3A-related intellectual disability syndrome due to a point mutation by St James's Hospital, Trinity College Dublin ... SIN3A antibody ... SIN3A antibody detects SIN3A protein at nucleus on rat fore brain by immunohistochemical analysis. Sample: Paraffin-embedded rat fore brain. File:Protein SIN3A PDB 1g1e.png. Size of this preview: 702 × 599 pixels ... SIN3A protein. Based on PyMOL rendering of PDB [http://www.pdb.org/pdb ... Jun 13, 2020 ... Let c=cos(A), s=sin(A), C=cos(2A), and S=sin(2A). Then. cos(3A)=Cc−Ssandsin(3A)=Sc+sC. so the numerator on the LHS is. Sin3a deletion in mice causes CDH, lung hypoplasia, defects in cell cycling, and pulmonary hypertension. • Use Sin3a genetic targets as a guide to improve lung ... Jan 12, 2021 ... Abstract. Witteveen-Kolk syndrome (OMIM 613406) is a recently defined neurodevelopmental syndrome caused by heterozygous loss-of-function ... Description. Sin3A is encoded by this gene is a transcriptional regulatory protein. It contains paired amphipathic helix (PAH) domains, which are important ... ▽ Description. SAP130 is a subunit of the histone deacetylase (see HDAC1; 601241)-dependent SIN3A (607776) corepressor complex (Fleischer et al., 2003).