Mối liên hệ giữa sin3a và các vấn đề về khoa học xã hội.

Oct 2, 2018 ... Here we report the identification of a highly conserved SID in the 5-methylcytosine dioxygenase, Tet1 (Tet1-SID), which interacts directly with the PAH1 domain ... Aug 1, 2023 ... SIN3A defects associated with syndromic congenital hypogonadotropic hypogonadism: an overlap with Witteveen-Kolk syndrome. PA1-870 detects mSin3A from human and mouse tissues and cells. PA1-870 has been successfully used in Western blot, ICC/IF ChIP, IHC-P and immunoprecipitation ... ... Sin3A, Rab40C, Rad50, and Ube2i were necessary for both AHR expression and ... Sin3A, from which we found that Sin3A physically associates with the 5 ... Witteveen-Kolk syndrome (WITKOS) is an autosomal dominant disorder with characteristic distinctive facial features, microcephaly, short stature, and mildly ... Feb 27, 2024 ... Provided the recent observation that the SIN3A histone deacetylase complex reduces transcription-replication conflicts, we explore the role of ... HDAC1 activity [29] and the Sin3A complex [30] are also required for full transcriptional activity of interferon-α responsive genes and Nanog promoter, ... Jan 24, 2022 ... Conclusions. Our studies revealed that Sin3a was a novel mediator of MET during early reprogramming, where Sin3a functioned as an epigenetic ... Jun 28, 2017 ... Sin3a is a central component of a class of histone deacetylase‐containing transcriptional co‐regulatory complexes. In this issue of The EMBO ... function. Acts as a transcriptional repressor. Corepressor for REST. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities ...