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... Sin3A corepressor complex and targets Sin3A. SAP30L interacts with members of the Sin3A corepressor complex and targets Sin3A to the nucleolus. Nucleic Acids ... Jan 12, 2021 ... Abstract. Witteveen-Kolk syndrome (OMIM 613406) is a recently defined neurodevelopmental syndrome caused by heterozygous loss-of-function ... Sin3A Rabbit pAb (A1577) ... US orders can be delivered next day. ... The human genetic variant rs6190 unveils Foxc1 and Arid5a as novel pro-metabolic targets of ... Feb 3, 2025 ... ... Sin3a as a novel transcriptional regulator of β-cell mass adaptation. β-Cell–specific Sin3a knockout animals showed profound diabetes due to ... ... SIN3A and MAN2C1 resulting in Witteveen-Kolk syndrome ... This deletion is anticipated to result in production of a chimeric SIN3A::MAN2C1 protein which would ... Jun 28, 2017 ... Sin3a is a central component of a class of histone deacetylase‐containing transcriptional co‐regulatory complexes. In this issue of The EMBO ... May 8, 2018 ... LSD1 coordinates with the SIN3A/HDAC complex and maintains sensitivity to chemotherapy in breast cancer PA1-870 detects mSin3A from human and mouse tissues and cells. PA1-870 has been successfully used in Western blot, ICC/IF ChIP, IHC-P and immunoprecipitation ... Detects human and mouse SIN3A in Western blots. Source: Polyclonal Goat IgG. Purification: Antigen Affinity-purified. Immunogen: E. coli-derived recombinant ... HDAC1 activity [29] and the Sin3A complex [30] are also required for full transcriptional activity of interferon-α responsive genes and Nanog promoter, ...