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SIN3A (SIN3 Transcription Regulator Family Member A) is a protein coding gene located on human chromosome 15q24.2. SIN3A is also known as WITKOS. Feb 27, 2024 ... Provided the recent observation that the SIN3A histone deacetylase complex reduces transcription-replication conflicts, we explore the role of ... Apr 18, 2020 ... Share your videos with friends, family, and the world. SIN3A ... Paired amphipathic helix protein Sin3a is a protein that in humans is encoded by the SIN3A gene. SIN3A. Available structures. PDB, Ortholog ... Sin3a deletion in mice causes CDH, lung hypoplasia, defects in cell cycling, and pulmonary hypertension. • Use Sin3a genetic targets as a guide to improve lung ... Sin3a plays a critical role in the maintenance of Treg identity and function and is essential for the expression and stability of Foxp3. Oct 2, 2018 ... Here we report the identification of a highly conserved SID in the 5-methylcytosine dioxygenase, Tet1 (Tet1-SID), which interacts directly with the PAH1 domain ... SIN3A (SIN3 Transcription Regulator Family Member A) is a Protein Coding gene. Diseases associated with SIN3A include Witteveen-Kolk Syndrome and Chromosome ... function. Acts as a transcriptional repressor. Corepressor for REST. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities ... Here, we show that FOXK2 binds to the SIN3A and PR-DUB complexes. The PR-DUB complex contains the important tumour suppressor protein, the deubiquitinase ...