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SIN3A (SIN3 Transcription Regulator Family Member A) is a protein coding gene located on human chromosome 15q24.2. SIN3A is also known as WITKOS. 4 days ago ... SIN3A, generally regarded as a transcriptional repressor, is required for induction of gene transcription by the aryl hydrocarbon receptor. Aug 14, 2017 ... We demonstrated that the FOXN3-NEAT1-SIN3A complex promotes EMT and invasion of breast cancer cells in vitro as well as dissemination and ... A few children are known to have inherited a pathogenic variant of the SIN3A gene form a mildly affected parent. The risk of having another child affected by a ... function. Acts as a transcriptional repressor. Corepressor for REST. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities ... Witteveen-Kolk syndrome (WITKOS) is an autosomal dominant disorder with characteristic distinctive facial features, microcephaly, short stature, and mildly ... Fam60a defines a variant Sin3a‐Hdac complex in embryonic stem cells required for self‐renewal. The EMBO Journal. Sin3a is the central scaffold protein of ... Sin3A Rabbit pAb (A1577) ... US orders can be delivered next day. ... The human genetic variant rs6190 unveils Foxc1 and Arid5a as novel pro-metabolic targets of ... Jun 14, 2019 ... Abstract. STAT3 can mediate epigenetic silencing of tumor suppressor genes (TSG). However, little is known about the molecular mechanisms ... File:Protein SIN3A PDB 1g1e.png. Size of this preview: 702 × 599 pixels ... SIN3A protein. Based on PyMOL rendering of PDB [http://www.pdb.org/pdb ...