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Detects human and mouse SIN3A in Western blots. Source: Polyclonal Goat IgG. Purification: Antigen Affinity-purified. Immunogen: E. coli-derived recombinant ... Aug 2, 2018 ... Our data suggest that Fam60a is required for proper embryogenesis, at least in part as a result of its regulation of DNA methylation at specific gene promoters. Jun 14, 2019 ... Abstract. STAT3 can mediate epigenetic silencing of tumor suppressor genes (TSG). However, little is known about the molecular mechanisms ... ▽ Description. SAP130 is a subunit of the histone deacetylase (see HDAC1; 601241)-dependent SIN3A (607776) corepressor complex (Fleischer et al., 2003). Unfollow This Gene ... Click here to learn more about how to cite ClinGen and to see a list of the external resources utilized. The information on this website is ... Feb 9, 2024 ... We observe that Sin3A protein is enriched at replicating DNA in the presence of hydroxyurea. In this situation, Sin3A-depleted cells show ... Feb 27, 2024 ... Provided the recent observation that the SIN3A histone deacetylase complex reduces transcription-replication conflicts, we explore the role of ... Witteveen-Kolk syndrome (WITKOS) is an autosomal dominant disorder with characteristic distinctive facial features, microcephaly, short stature, and mildly ... Nov 1, 2014 ... ... Sin3A Associated Protein 130 (SAP130). 2. Previous1Next. Citation. Dessen P. SAP130 (Sin3A associated protein 130). Atlas Genet Cytogenet Oncol ... Jul 15, 2015 ... Here, we describe the mechanism of assembly of the mammalian Sin3L/Rpd3L complex facilitated by Sds3, a conserved subunit deemed critical for proper assembly.